| 
 Formula Ingredient Deck 
 | 
 Benefits Of Each Ingredient  
 | 
| 
 Calcium Carbonate 
 | 
- May support bone health, muscle function, and cardiovascular health (36,37)
 
-  Regulates processes of bone resorption, mineralization, and fracture repair (36,37).
 
- Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). 
 
- May support reduced prevalence of preeclampsia (36,37).
 
 
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| 
 Vitamin B6 
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- Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40)
 
- May support reduced plasma glucose (blood sugar levels) via inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).
 
- Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).
 
- May support blood sugar regulation in women with gestational diabetes (40).
 
- Cofactor for enzymes involved in DNA metabolism (40).
 
 
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| 
 Magnesium 
 | 
- May support optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91).
 
- Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91).
 
- May support reduced systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).
 
- May support reduced peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91).
 
 
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| 
 L-Tryptophan 
 | 
- May support decreased anxiety,  positive mood, improved gut brain axis cross talk, and an improved sleep cycle (259,260). 
 
- Decreases anxiety via increases in 5 HTP (259, 260).
 
- May support improved circadian rhythm via increased natural melatonin production (259,260).
 
- 
May support gut brain axis via natural increased production of serotonin in gut neurons (260). 
 
 
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| 
 Goji Berry 
 | 
- May support immune health, vision health, immune health, and aids as a neuroprotective agent (261,262).
 
- May support immune function via carotenoid and polyphenolic free radical scavenging capabilities, reduced DNA damage, and reduced inflammatory cytokines (261).
 
- May support vision health via ocular neuroprotective effects zeaxanthin content (found in goji berry) (262).
 
- May support cognitive function via increased neuronal protection with potent ameliorative effects on neuronal oxidative stress, inflammation, apoptosis and neuronal cell death (262).
 
 
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| 
 Chamomile 
 | 
- May support  healthy sleep, relaxation, reduced anxiety, and antioxidant support (251,252,253).
 
- May support  antioxidant function due to high levels of quercetin (flavonoid antioxidant) (251,252,253).
 
- May support  sleep via increases in parasympathetic (relaxation mode) activity, increased benzodiazepine-like hypnotic activity (sleep inducer), and attachment to GABA receptors (251,252,253).
 
 
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| 
 Lemon Balm 
 | 
- May support  healthy sleep, relaxation, reduced anxiety, and antioxidant support (254,255).
 
- 
May support antioxidant function via ability to scavenge free radicals, reduce oxidative stress, increased glutathione production (master antioxidant) combat DNA damage (254,225).
 
- May support relaxed sleep via enhanced REM cycles reduced stress at bedtime (254,225).
 
 
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| 
 Passion Flower 
 | 
- May support reduced stress, enhanced sleep, and improved mood (248).
 
- 
May support positive mood and improved sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (248).
 
 
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| 
 L-Taurine 
 | 
- May support hydration, increased energy, antioxidant function, and increases fat metabolism during aerobic exercise (242,243).
 
- May support  antioxidant function via combating reactive oxygen species (243).
 
- May support increased fat metabolism during exercise via enhanced mitochondrial fatty acid oxidation (cells using fat as fuel) (242).
 
 
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| 
 Hops 
 | 
- 
May support reduced prevalence of depression, anxiety, reduced triglycerides and increased positive mood (246,247). 
 
 
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| 
 St. John’s Wort 
 | 
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| 
 GABA 
 | 
- 
May support  relaxation, positive mood, increased memory, reduced anxiety, blood sugar regulation, and increased growth hormone production (102). 
 
 
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| 
 Skullcap 
 | 
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| 
 L-Theanine 
 | 
- Unique non-protein amino acid found in green tea (Camellia sinensis) (53).
 
- May support  mood, mental clarity, and cognitive health, memory, and is a natural anti-depressant/neuroprotective agent (53).
 
 
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| 
 Ashwagandha 
 | 
- May support cardiovascular, hormonal, immune, healthy weight loss, mood, and optimized sleep (82,83).
 
- 
May support reduced stress hormone cortisol resulting in improved body composition, sex hormone profile, and mood (82,83).
 
- May support improved exercise performance via increased V02 max, muscular endurance, muscle hypertrophy (muscle growth), and decreased muscular fatigue (83). 
 
- May support improved quality of sleep by enhancing sleep recovery, reducing plasma cortisol concentrations, and enhancing REM sleep cycles (83).
 
- May support  hormonal and immune health via reduced production of inflammatory molecules (reactive oxygen species) and simultaneous increases in sex hormones (84).
 
 
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| 
 Inositol 
 | 
- May support liver detoxification, reduced prevalence of metabolic syndrome, and aids as an antioxidant (221).
 
- 
May support reduced prevalence of metabolic syndrome via reduced levels of triglycerides, total- and LDL-cholesterol (221).
 
 
- May support antioxidant function via reduced levels of reactive oxygen species and inflammatory markers (interleukin 6) (222).
 
 
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| 
 5-HTP 
 | 
- May support healthy sleep patterns, mood, reduced anxiety, and supports the gut brain axis (261).
 
- May support healthy sleep patterns via enhanced circadian rhythm and increased natural melatonin production (261).
 
- May support gut brain axis via natural increased production of serotonin (neurotransmitter) in gut neurons (260, 261).
 
 
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| 
 Melatonin 
 | 
- May support healthy sleep patterns, immune function, and antioxidant support (256,257, 258).
 
- May support healthy circadian rhythms, and improves the onset, duration, and quality of sleep.
 
- May support immune function via improved free radical scavenging capacity (258).
 
 
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| 
 Valerian Root 
 | 
- May support reduced stress, enhanced sleep, and improved mood (244,245).
 
- May support enhanced positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (244, 245). 
 
 
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