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Formula Ingredient Deck
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Benefits Of Each Ingredient
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Vitamin A (beta carotene)
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May support vision health, skin health, immune health, and increases antioxidant support (182, 183).
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May support antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182, 183).
- May support visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183).
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Vitamin C
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May support immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98).
- May support immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).
- May support fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).
- May support accelerated bone healing after a fracture, increased type I collagen synthesis, and reduced oxidative stress (inflammation) (98).
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Calcium Carbonate
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May support bone health, muscle function, and cardiovascular health (36,37).
- Regulates processes of bone resorption, mineralization, and fracture repair (36,37).
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Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37).
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May support reduced prevalence of preeclampsia (36,37).
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Vitamin D3
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- May support exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, increased strength, and positive mood (77,78,79).
- May support hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone based negative feedback loop reactions (77,78).
- May support cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78).
- May support exercise recovery via reduced post exercise inflammation and muscle damage (77,78).
- May support sexual health via increased activity of Vitamin D receptor activity of testosterone production (79).
- May support immune function via decreases of inflammatory cytokines and aiding immune cells (77,78).
- May support joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78).
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Vitamin E
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- May support immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208)
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May support immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204).
- May support cardiovascular health via reduced cholesterol (204).
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May support cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208).
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Vitamin B1 (Thiamine)
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- May support aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94).
- May support cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95).
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Vitamin B2 (Riboflavin)
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- May support conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93).
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Vitamin B3 (Niacin)
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- Major B vitamin that may support cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very-low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9).
- Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9).
- Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9).
- May support healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9).
- May support reduced prevalence of pellagra, nervous anorexia, and Crohn’s disease (10, 11).
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Vitamin B6
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- Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40).
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May support reduced plasma glucose (blood sugar levels) via inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).
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Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).
- May support blood sugar regulation in women with gestational diabetes (40).
- Cofactor for enzymes involved in DNA metabolism (40).
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Vitamin B12
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May support proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53).
- Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51).
- May support reduced vitamin b-12 deficiency pathologies such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53).
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Zinc
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May support immune function, skin health, cognitive function, and vision (172,173).
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May support stimulation of the innate and adaptive immune system (172,173).
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May support the activation of lymphocytes and activation of innate T cell-mediated immunity (172,173).
- May support cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).
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Biotin
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May support conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214)
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May support glucose breakdown into skeletal muscle tissue (213,214).
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Vitamin B5
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May support energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96).
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Magnesium
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- May support optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91).
- Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91).
- May support reduced systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).
- May support reduced peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91).
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Copper
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May support healthy blood sugar levels, energy metabolism and cholesterol management (143,144).
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Selenium
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- May support antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146).
- May support reduced prevelance of atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147).
- May support thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146).
- Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147).
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Manganese
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May support enzymatic antioxidant reactions, increased bone mineral density, and blood sugar regulation (148,149).
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Molybdenum
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- May support increased enzymatic reactions involved in sulfite metabolism and detoxification (150).
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Chromium
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May support insulin function, reduced cholesterol, improved blood sugar regulation, and may lower cholesterol (218,219).
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Lutein
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- A carotenoid that may support vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156).
- May support increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156).
- May support visual health via increased lutein concentration in the macular layer of the retina, reduced susceptibility to age-related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156).
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Lycopene
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May support prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193).
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May support reduced inflammation via scavenging of free radicals and reduces oxidative damage of DNA. (191,192,193).
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Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193).
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Spirulina
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May support reduced cholesterol, blood pressure, blood sugar regulation, reduces inflammation, reduced body fat, and supports antioxidant function (301, 302).
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Goldenseal Root
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- May support digestive health, antibacterial activity, and antioxidant support (201, 202).
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May support antioxidant function via increased levels of berberine (alkaloid) (201,202).
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Echinacea
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- May support immune health via increased antiviral, anti-microbial, antioxidant capacity, (159,160).
- May support immune health via decreased impro-inflammatory markers (cytokines IL-6, IL-8, and TNF) (159,160).
- May support adaptive and innate immunity via increased monocytes, neutrophils, natural killer cells, and CD8 T cells (159,160).
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Garlic
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May support cardiovascular health, immune health, joint health, reduced inflammation, gut health, and enhanced antibacterial activity (161).
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May support cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161).
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May support joint health via reduced NF-κB activation (inflammation) in human fibroblasts cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162).
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May support gut health via increased prebiotic properties, increased microbiome population, and increased Lactobacillus and Clostridia species (163).
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May support immune health via a reduction in inflammatory markers (CRP, TNF, IL-6) (164).
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Green Tea Extract
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- A potent polyphenolic antioxidant that may support blood pressure, insulin sensitivity, and metabolic health (25).
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High in ECGC (epigallocatechin gallate) (25).
- ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise. (25).
- Potent anti-inflammatory compound that may support glutathione production and inhibition of pro-inflammatory markers (cytokines). (26).
- May support reduced oxidative stress (chronic inflammation in the body) (26).
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Hawthorn Berries
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- May support cardiovascular health and combats metabolic syndrome (165).
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May support cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165).
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Cinnamon Bark Extract
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- May support blood sugar regulation and cardiovascular health (166).
- May support decreased levels of fasting plasma glucose, total cholesterol, LDL-C, triglyceride levels, and an increase in HDL-C levels (166).
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May support improved blood sugar regulation by improving insulin sensitivity and enhanced glucose uptake (166).
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Bilberry Fruit Extract
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- May support vision health, cardiovascular function, increased nitric oxide production, blood sugar regulation, and antioxidant support (167,168).
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Grape Seed Extract
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- May support increased nitric oxide production, reduces blood pressure, reduces DNA damage, increases collagen production, increases bone strength, and aids as a neuroprotective agent (31).
- May support antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31).
- May support cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31).
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Black Currant
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- May support immune function via high levels of polyphenols and reduction of inflammation (169).
- May support cardiovascular health via reductions in LDL Cholesterol (169).
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Pomegranate Extract
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- May support reduced blood pressure, increased nitric oxide production, immune health, blood sugar regulation, prostate health, gut health and aids as an antimicrobial compound (170).
- May support prostate health via high polyphenolic antioxidant levels (three times the antioxidant activity of green tea) that protect the prostate gland from inflammation (170).
- May support reduced blood pressure via increased nitric oxide production, increased cardiac output (blood flow), and reduced cholesterol levels (170.
- May support digestive health via combating inflammatory bowel disease (171).
- May support immune health via reduced inflammatory cytokines (markers of inflammation) throughout the body (171).
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